产品
编 号：F422132
分子式：C8H6N4O5
分子量：238.16
分子式：C8H6N4O5
分子量：238.16
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
320
In-stock
1g
400
In-stock
5g
640
In-stock
结构图
CAS No: 67-20-9
产品详情
生物活性：
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
体内研究：
1.19Nitrofurantoin pharmacokinetic effects in SD Rats. Parameters10 mg/kg p.o.2 mg/kg i.v.
AUC0-720 (μg/mL·min)306
AUC0-120 (μg/mL·min)90.3
AUC0-∞ (μg/mL·min)34491.5
Cmax (μg/mL)1.01
CL/F or CL (ml/min/kg)31.022.7
t1/2 (min)16623.6
Bioavailability (%)60.1
体外研究：
Nitrofurantoin (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates.
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections.
体内研究：
1.19Nitrofurantoin pharmacokinetic effects in SD Rats. Parameters10 mg/kg p.o.2 mg/kg i.v.
AUC0-720 (μg/mL·min)306
AUC0-120 (μg/mL·min)90.3
AUC0-∞ (μg/mL·min)34491.5
Cmax (μg/mL)1.01
CL/F or CL (ml/min/kg)31.022.7
t1/2 (min)16623.6
Bioavailability (%)60.1
体外研究：
Nitrofurantoin (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates.
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