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编 号：F422083
分子式：C7H9ClN2O4S2
分子量：284.74
分子式：C7H9ClN2O4S2
分子量：284.74
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CAS No: 671-88-5
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生物活性：
Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. Disulfamide leads to diuresis by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal tubule.
体内研究：
Disulfamide (intraperitoneal injection, 200 mg/kg, once) has potential blood glucose raising properties in male Wistar rats.Animal Model:Male Wistar rats weighing between 200-300 g
Dosage:200 mg/kg
Administration:Intraperitoneal injection; once
Result:Resulted in elevated blood sugar levels from an initial blood glucose concentration of 143.1 mg/100 mL to a one hour later final concentration of 194.6 mg/100 mL, an increase of 36%.
Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. Disulfamide leads to diuresis by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal tubule.
体内研究：
Disulfamide (intraperitoneal injection, 200 mg/kg, once) has potential blood glucose raising properties in male Wistar rats.Animal Model:Male Wistar rats weighing between 200-300 g
Dosage:200 mg/kg
Administration:Intraperitoneal injection; once
Result:Resulted in elevated blood sugar levels from an initial blood glucose concentration of 143.1 mg/100 mL to a one hour later final concentration of 194.6 mg/100 mL, an increase of 36%.
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