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编 号:F048951
分子式:C21H22N2O2
分子量:334.41
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生物活性:
SKF96067 is a reversible inhibitor of the gastric H+/K+-ATPase.

体外研究:
SKF96067 inhibits K+-stimulated ATPase activity competitively with respect to the activating action K+, with a Ki value of 0.39 ± 0.05 μM. SKF96067 also inhibits hydrogen ion transport. SKF96067 inhibits ATPase activity with an IC50 value of 60 ± 10 μM at pH 7.0, in the presence of 100 mM NaCl and 1 mM KCl.
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