产品
编 号:F419700
分子式:C20H27NO4S
分子量:377.5
产品类型
结构图
CAS No: 66264-77-5
联系客服
产品详情
生物活性:
Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity.
体内研究:
Sulfinalol shows direct vasodilator activity and antihypertensive activity.Animal Model:Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)
Dosage:0-100 μg
Administration:Intraarterial injection
Result:Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.
Animal Model:Male spontaneously hypertensive rats (SHR)
Dosage:2.5 mg/kg
Administration:Oral administration
Result:Reduced pressure of conscious spontaneously hypertensive rats.