产品
编 号：F419661
分子式：C13H15Cl2N3
分子量：284.18
分子式：C13H15Cl2N3
分子量：284.18
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
250mg
760
In-stock
结构图
CAS No: 66246-88-6
产品详情
生物活性：
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats.
体内研究：
Penconazole (67 mg/kg; i.p.; every 2 days during 9 days) induces oxidative stress in rat cerebrum and cerebellum tissues.Penconazole has the ability to induce oxidative damage in the brain of adult rats, as evidenced by an increase of lipid peroxidation and protein oxidation, in addition to the perturbations in the enzymatic and nonenzymatic antioxidant status. Penconazole also affects the cholinergic system, activities of membrane-bound ATPases, and brain histoarchitecture. Penconazole is a potential neurotoxicant pesticide that exerts its neurotoxic effects via the generation of oxidative stress. Penconazole causes a significant inhibition of AChE activity in the cerebrum (11%) and cerebellum (25%) of adult rats.Animal Model:Twelve male Wistar rats
Dosage:67 mg/kg
Administration:I.p.; every 2 days during 9 days
Result:A significant increase was obtained in the absolute and relative weights of the cerebrum and cerebellum, respectively.
Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats.
体内研究：
Penconazole (67 mg/kg; i.p.; every 2 days during 9 days) induces oxidative stress in rat cerebrum and cerebellum tissues.Penconazole has the ability to induce oxidative damage in the brain of adult rats, as evidenced by an increase of lipid peroxidation and protein oxidation, in addition to the perturbations in the enzymatic and nonenzymatic antioxidant status. Penconazole also affects the cholinergic system, activities of membrane-bound ATPases, and brain histoarchitecture. Penconazole is a potential neurotoxicant pesticide that exerts its neurotoxic effects via the generation of oxidative stress. Penconazole causes a significant inhibition of AChE activity in the cerebrum (11%) and cerebellum (25%) of adult rats.Animal Model:Twelve male Wistar rats
Dosage:67 mg/kg
Administration:I.p.; every 2 days during 9 days
Result:A significant increase was obtained in the absolute and relative weights of the cerebrum and cerebellum, respectively.
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