产品
编 号:F419334
分子式:C19H26I3N3O9
分子量:821.14
产品类型
结构图
CAS No: 66108-95-0
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产品详情
生物活性:
Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging.
体内研究:
Iohexol (0.25-4 mL/kg, p.o., weekly) 浓度为 0.5-2.0 mL/kg 时,可促进狗肠段的分化。Iohexol (64.7 mg/kg,静脉注射) 可用于估算健康或患有慢性肾病 (CKD) 的犬的肾小球滤过率 (GFR)。Animal Model:Healthy dogs
Dosage:0.25-4 mL/kg
Administration:Oral gavage (p.o.), weekly
Result:Peaked the iohexol serum concentrations between 2 and 4 hours.Reduced radiolucency after application of 0.25 mL/kg and 4 mL/kg.Included watery diarrhea after ingestion of 4 mL/kg.
体外研究:
Iohexol (150 mg I/mL, 0-24 h) 抑制 NRK 52-E 的细胞活力。