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编 号:F416726
分子式:C25H33ClN2O7
分子量:508.99
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Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.

体内研究:
Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats.
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