产品
编 号：F047128
分子式：C19H27N3O5S2
分子量：441.56
分子式：C19H27N3O5S2
分子量：441.56
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
164
In-stock
5mg
328
In-stock
10mg
572
In-stock
50mg
1644
In-stock
结构图
CAS No: 115256-11-6
产品详情
生物活性：
Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease.
体内研究：
Dofetilide (3~100 μg/kg；iv) 通过选择性延长激活复极化间隔来增加复极化时间，激活时间不变。 Dofetilide 被 CYP3A4 代谢为混合物然后由肾脏排泄的非活性极性代谢物。Animal Model:Adult beagle dogs (13-15 kg)
Dosage:3~100 μg/kg
Administration:I.v.
Result:Increased repolarisation time via a selective prolongation of activation repolarisation interval, activation time being unchanged.
Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease.
体内研究：
Dofetilide (3~100 μg/kg；iv) 通过选择性延长激活复极化间隔来增加复极化时间，激活时间不变。 Dofetilide 被 CYP3A4 代谢为混合物然后由肾脏排泄的非活性极性代谢物。Animal Model:Adult beagle dogs (13-15 kg)
Dosage:3~100 μg/kg
Administration:I.v.
Result:Increased repolarisation time via a selective prolongation of activation repolarisation interval, activation time being unchanged.
产品资料
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