产品
编 号:F416317
分子式:C10H14O
分子量:150.22
产品类型
结构图
CAS No: 6485-40-1
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产品详情
生物活性:
(-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae.
体内研究:
(-)-Carvone (5% in absolute ethanol v/v, 20 μL; application to the thoraces ventral surfaces) inhibits AChE such as horse serum cholinesterase, house fly head cholinesterases, and head and thorax cholinesterases from the Madagascar roach in vitro.(-)-Carvone (0.05%-0.1% w/v; p.o.; 7 d) inhibits E. insulana larvae growth, decreases weight of larvae.Animal Model:Female roaches (Gromphadorhina portentosa) (6.4 g-6.8 g)
Dosage:5% in absolute ethanol v/v, 20 μL
Administration:Application to the ventral surfaces of their thoraces; decapitated and crude at various time intervals (0, 2, 4, 5, 20, 24, and 26 hr)
Result:Inhibited the activity of AChE in the extracts of both the head and thorax.
体外研究:
(-)-Carvone (3.04 mM; 30 min) inactivates eel AChE with Ki value of 2.19 mM.