产品
编 号:F416184
分子式:C14H8ClNNa2O4
分子量:335.65
产品类型
结构图
CAS No: 64808-48-6
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产品详情
生物活性:
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent.
体内研究:
Lobenzarit disodium (CCA; 10 and 50 mg/kg; i.p.; daily for 7 days) 通过激活抑制性 T 淋巴细胞发挥其抗关节炎作用。Animal Model:Sprague-Dawley rats
Dosage:10 and 50 mg/kg
Administration:IP; daily for 7 days
Result:Showed anti-arthritic effect, but had no therapeutic effect in arthritic rats which were depleted of T lymphocytes.
体外研究:
Lobenzarit disodium (CCA) 抑制活性氧诱导的化学发光,IC50 为 1.6 μM。Lobenzarit disodium (0.3-300 μM) 抑制过氧化脂质生成和紫外线照射诱导的 IgG 改变。