产品
编 号:F415466
分子式:C15H12O2
分子量:224.25
产品类型
结构图
CAS No: 644-78-0
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产品详情
生物活性:
2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB.
体外研究:
2-Hydroxychalcone inhibits invasion of triple negative breast cancer cells.2-hydroxychalcone inhibits the adhesion of peripheral neutrophils to the endothelial cell monolayers by inhibiting the expression of ICAM-1, VCAM-1, and E-selectin in a concentration-dependent manner.