产品
编 号:F005262
分子式:C14H11F3N2O
分子量:280.25
产品类型
结构图
CAS No: 1011244-72-6
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产品详情
生物活性:
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM. Teriflunomide impurity 3 is less active against COX-2 (IC50>100 μM).
体外研究:
Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide; compound 11q) is an amide-bond-reversed compound bearing trifluoromethyl and amino substituents showed potent COX-1-selective inhibitory activity.