产品
编 号：F414831
分子式：C11H10N4OS
分子量：246.29
分子式：C11H10N4OS
分子量：246.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
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10mg
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25mg
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50mg
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结构图
CAS No: 64232-83-3
产品详情
生物活性：
L189 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer.
体外研究：
L189 inhibits DNA Ligase I, III and IV activity with IC50 values of 5 μM, 9 μM and 5 μM, respectively.L189 (5 μM, 48 h) bring good anti-proliferation activity preferentially and cause cell death by creating a cytotoxic environment.L189 (5 μM, 48 h) reduces HeLa nuclear staining along with TMZ.L189 (5 μM, 48 h) enhances TMZ-induced HeLa growth arrestwhen along with TMZ that possibly in G2/M cell cycle phase without employing cell death mechanisms.
L189 is a DNA ligase inhibitor. L189 has inhibition effect for DNA Ligase I, III and IV with IC50 values of 5 μM, 9 μM and 5 μM, respectively. L189 has no cytotoxicity and individually increase cell death. L189 can be used for the research of cancer.
体外研究：
L189 inhibits DNA Ligase I, III and IV activity with IC50 values of 5 μM, 9 μM and 5 μM, respectively.L189 (5 μM, 48 h) bring good anti-proliferation activity preferentially and cause cell death by creating a cytotoxic environment.L189 (5 μM, 48 h) reduces HeLa nuclear staining along with TMZ.L189 (5 μM, 48 h) enhances TMZ-induced HeLa growth arrestwhen along with TMZ that possibly in G2/M cell cycle phase without employing cell death mechanisms.
产品资料
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