产品
编 号：F414461
分子式：C10H13N3O2
分子量：207.23
分子式：C10H13N3O2
分子量：207.23
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
213
In-stock
5mg
560
In-stock
10mg
960
In-stock
50mg
2320
In-stock
100mg
2800
In-stock
结构图
CAS No: 64091-91-4
产品详情
生物活性：
NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure.
体外研究：
NNK (100 pM; 0-60 min) stimulates activation of PKCα and MAPKs ERK1/2 that directly induce c-Myc phosphorylation.NNK (100 pM; 96 hours) enhances proliferation of cells expressing WT but not AA c-Myc mutant.
NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα. NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure.
体外研究：
NNK (100 pM; 0-60 min) stimulates activation of PKCα and MAPKs ERK1/2 that directly induce c-Myc phosphorylation.NNK (100 pM; 96 hours) enhances proliferation of cells expressing WT but not AA c-Myc mutant.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备