产品
编 号：F414074
分子式：C15H22O5
分子量：282.33
分子式：C15H22O5
分子量：282.33
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
100
In-stock
10mg
120
In-stock
50mg
240
In-stock
100mg
384
In-stock
200mg
536
In-stock
500mg
893
In-stock
结构图
CAS No: 63968-64-9
产品详情
生物活性：
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
体内研究：
Artemisinin (gavage; 20 mg/kg/day; for two weeks) 抑制 UMRC-2 异种移植肿瘤的生长。Animal Model:4-6 weeks old male nude mice
Dosage:20?mg/kg
Administration:gavage; every day for two weeks
Result:Suppressed UMRC-2 xenograft tumor growth.
体外研究：
Artemisinin (Qinghaosu) (25 or 50 μM; 24 hours) 浓度依赖性地抑制 Aβ25-35 诱导的 PC12 细胞毒性。 Artemisinin (1-100 μM; 24hours) 以剂量依赖性方式选择性地抑制癌细胞生长，其对 UMRC-2 细胞和 CAKI-2 细胞的 IC50 值分别为23.97, 31.30 μM。 Artemisinin (25, 50 μM; 24 hours) 以剂量依赖性方式抑制 UMRC-2 和 CAKI-2 细胞中 AKT 的磷酸化。
Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
体内研究：
Artemisinin (gavage; 20 mg/kg/day; for two weeks) 抑制 UMRC-2 异种移植肿瘤的生长。Animal Model:4-6 weeks old male nude mice
Dosage:20?mg/kg
Administration:gavage; every day for two weeks
Result:Suppressed UMRC-2 xenograft tumor growth.
体外研究：
Artemisinin (Qinghaosu) (25 or 50 μM; 24 hours) 浓度依赖性地抑制 Aβ25-35 诱导的 PC12 细胞毒性。 Artemisinin (1-100 μM; 24hours) 以剂量依赖性方式选择性地抑制癌细胞生长，其对 UMRC-2 细胞和 CAKI-2 细胞的 IC50 值分别为23.97, 31.30 μM。 Artemisinin (25, 50 μM; 24 hours) 以剂量依赖性方式抑制 UMRC-2 和 CAKI-2 细胞中 AKT 的磷酸化。
产品资料
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