产品
编 号:F413567
分子式:C63H113N11O12
分子量:1216.64
产品类型
结构图
CAS No: 63775-96-2
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产品详情
生物活性:
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc).
体内研究:
Cyclosporine D is a potent inhibitor in vivo of phorbol ester TPA-induced biological effects in mouse skin.
体外研究:
Cyclosporine D inhibits Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.