产品
编 号:F046248
分子式:C26H34N6O2S
分子量:494.65
产品类型
结构图
CAS No: 1149753-56-9
联系客服
产品详情
生物活性:
ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM.
体外研究:
ITK antagonist inhibits DT40 cell (IC50=4 nM) and shows IL-2 inhibition (IC50=20 nM).