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编 号：F046156
分子式：C14H16Cl2N4O3
分子量：359.21
分子式：C14H16Cl2N4O3
分子量：359.21
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CAS No: 114-90-9
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生物活性：
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated.
体内研究：
Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg afteradministration of sarin, and it reduces reduces acute toxicity of sarin was evaluated.Animal Model:NMRI male mice
Dosage:10 mg/kg
Administration:Intramuscular injection
Result:Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE).
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated.
体内研究：
Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg afteradministration of sarin, and it reduces reduces acute toxicity of sarin was evaluated.Animal Model:NMRI male mice
Dosage:10 mg/kg
Administration:Intramuscular injection
Result:Was effective in reactivating sarin-inhibited acetylcholinesterase (AChE).
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