产品
编 号:F046153
分子式:C53H86O21
分子量:1059.24
产品类型
结构图
CAS No: 114906-74-0
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产品详情
生物活性:
Ciwujianoside?C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax?henryi Harms. Ciwujianoside?C3 has anti-inflammatory effect and can reinforces object recognition memory.
体内研究:
Animal Model:Mice
Dosage:0.5 mg/kg
Administration:Oral administration; 0.5 mg/kg/day; 17 days
Result:Reinforced object recognition memory.
体外研究:
Ciwujianoside C3 相关抗体:Cell Viability AssayCell Line:RAW?264.7 cells
Concentration:10 μM, 20 μM and 40?μM
Incubation Time:24 hours
Result:Has no effect on cell cytotoxicity and inhibits NO production
Western Blot AnalysisCell Line:RAW?264.7 cells
Concentration:10 μM, 20 μM and 40?μM
Incubation Time:24 hours
Result:Decreases p-ERK and p-JNK expression.
RT-PCRCell Line:RAW?264.7 cells
Concentration:10 μM, 20 μM and 40?μM
Incubation Time:24 hours
Result:Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.