产品
编 号：F046033
分子式：C13H15NO4
分子量：249.26
分子式：C13H15NO4
分子量：249.26
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
168
In-stock
500mg
280
In-stock
1g
364
In-stock
5g
532
In-stock
结构图
CAS No: 1148-11-4
产品详情
生物活性：
Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research.
体内研究：
Carbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model.Animal Model:C57Bl/6J mice (4-week-old)
Dosage:60 mg/kg
Administration:Injection; once daily for 3 weeks
Result:Resulted significant reduction of erythrocytes prolidase activity.
体外研究：
Carbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients.Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition.
Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research.
体内研究：
Carbobenzoxyproline (60 mg/kg; injection; once daily; 3 weeks) serves as in vivo inhibitor of erythrocytes prolidase in mice model.Animal Model:C57Bl/6J mice (4-week-old)
Dosage:60 mg/kg
Administration:Injection; once daily for 3 weeks
Result:Resulted significant reduction of erythrocytes prolidase activity.
体外研究：
Carbobenzoxyproline (6 mM; 0-10 d; pH=6.0) causes mitochondrial depolarization and increases cellular death by 33% as reported for long-term culture of fibroblasts from prolidase deficiency (PD) patients.Carbobenzoxyproline (0, 1, 3, 6 mM; 1 min; pH=6.0) results fibroblasts prolidase (FBP) hydrolysis, shows linear competitive inhibition.
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