产品
编 号:F406306
分子式:C6H6IN
分子量:219.02
产品类型
结构图
CAS No: 615-43-0
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生物活性:
2-Iodoaniline (2-Iodophenylamine) is an aniline derivative, and has potential hepatotoxic and nephrotoxic activity.
体内研究:
2-Iodoaniline (1.0 mM/kg, 1.25 mM/kg for 2.5 mL; i.p.; single dose) exhibits hepatotoxic and nephrotoxic potential in Male Fischer 344 rats.Animal Model:Male Fischer 344 rats (185-260 g)
Dosage:1.0 mM/kg, 1.25 mM/kg for 2.5 mL
Administration:Intraperitoneal injection; single dose; monitored renal and hepatic function 24 h after treatment
Result:Induced oliguria, diminished kidney weight, tubular casts and decreased renal cortical slice accumulation of organic anions.Elevated plasma ALT/GPT activity and altered morphology in the centrilobular region.