产品
编 号:F405855
分子式:C19H25ClN2O
分子量:332.87
产品类型
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CAS No: 6138-79-0
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生物活性:
Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats.
体内研究:
Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats.Animal Model:Male Sprague-Dawley rat (300-350 g)
Dosage:292.81 μg/kg, 488.02 μg/kg, 733.60μg/kg, 1098.83 μg/kg, 1467.20 μg/kg
Administration:Intrathecal injection
Result:Elicited a dose-dependent spinal block.