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编 号:F405088
分子式:C11H18ClNO3
分子量:247.72
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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生物活性:
Methoxamine hydrochloride is a selective alpha1-adrenergic receptor agonist. Methoxamine hydrochloride causes vasoconstriction and increased peripheral vascular resistance. Methoxamine hydrochloride significantly increased the overflow of ATP, ADP and AMP, but not adenosine, by a prazosin-sensitive mechanism in the rabbit pulmonary artery.

体内研究:
Methoxamine (0.025 mg/kg; femoral vein) hydrochloride has a greater effect on peripheral resistance vessels than on Winkessel vessels in the rat systemic circulation.Animal Model:Male Wistar-Kyoto rats weighing 320-47 g ( based on the exponentially tapered T-tube model)
Dosage:0.025 mg/kg
Administration:Femoral vein
Result:Had a greater effect on the peripheral resistance vessels than on the Winkessel vessels in the rat systemic circulation.
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