产品
编 号:F405036
分子式:C9H7NO
分子量:145.16
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1g
144
In-stock
5g
320
In-stock
结构图
联系客服
产品详情
生物活性:
4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune.

体外研究:
4-Quinolone (Kynurine) promotes tumor cell survival and motility by suppressing antitumor immune responses through AhR in an autocrine/paracrine fashion. This system is particularly active in human brain tumors where the activation of AhR enhances the expression of TDO producing more kynurine and kynurinic acid. In the healthy human brain, very low levels of TDO exist, whereas, in human brain tumors, the TDO protein levels increase with malignancy.
产品资料