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编 号:F404809
分子式:C4H10Na2O8
分子量:232.1
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5g
280
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生物活性:
Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications.

体内研究:
L-Tartaric acid (80-240 mg/kg; 口服给药; 单剂量) 在 L-NAME (60 mg/kg) 诱导的高血压小鼠中可以降低小鼠的血压。Animal Model:Hypertensive Wistar rat model
Dosage:80 mg/kg, 240 mg/kg
Administration:Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result:Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.

体外研究:
L-Tartaric acid (1.66-6.64 mM) 显著降低 NEP 和 KCL 诱导的主动脉环血管收缩,EC50 分别为 4.119 mM 和 4.00 mM。
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