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编 号:F403436
分子式:C27H30N4O
分子量:426.55
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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Oxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.
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