产品
编 号:F403268
分子式:C22H24N2O8
分子量:444.43
产品类型
结构图
CAS No: 60-54-8
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产品详情
生物活性:
Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections.
体内研究:
Tetracycline (3 mg/kg;每 12 小时腹腔注射一次直至存活) 使菌血症小鼠存活。Animal Model:Female ICR mice weight 30 to 40 g with V.vulnificus strain B3547 infection
Dosage:3 mg/kg
Administration:Intraperitoneal injection; 3 mg/kg every 12h until survive
Result:Inhibited the growth of human CNE-2 xenografts in nude mice.
体外研究:
Tetracycline 显示出对 V. vulnlflcus 菌株 B3547 的敏感性,MIC 值为 0.5 g/mL。 Tetracycline 抑制L-淀粉样蛋白聚集体的形成并分解预先形成的原纤维。