产品
编 号:F402597
分子式:C10H14N4O3
分子量:238.24
产品类型
结构图
CAS No: 603-00-9
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产品详情
生物活性:
Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator.
体内研究:
Proxyphylline exhibits bronchodilatory effect. Proxyphylline inhibits cAMP and cGMP hydrolysis in human lung tissue. The apparent inhibition constant of proxyphylline is 0.06-0.7 mM at low cAMP concentrations and it is 1.0 mM at high cAMP concentrations.
体外研究:
Proxyphylline has shown vasodilatory and cardiac stimulatory effects. Proxyphylline produces an increase in the coronary flow associated with a definite positive inotropic effect. Proxyphylline inhibits tracheal PDE-activity and half-maximum relaxation of tracheal smooth muscle is obtained with 100 μg/mL proxyphylline