产品
编 号：F402277
分子式：C7H10NNaO5
分子量：211.15
分子式：C7H10NNaO5
分子量：211.15
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5g
100
In-stock
结构图
CAS No: 6018-19-5
产品详情
生物活性：
Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate is para-aminosalicylic acid (PAS), a dihydrofolate reductase (DHFR) inhibitor and antituberculous agent. PAS is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity.
体内研究：
Sodium 4-aminosalicylate dihydrate
体外研究：
Sodium 4-aminosalicylate dihydrate 抑制结核分枝杆菌 H37Rv 生长，MIC 值为 0.4 μM。Sodium 4-aminosalicylate (10 μM-0.1 mM；3 h) 显著抑制牛分枝杆菌中的 rDHFR 活性。
Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate is para-aminosalicylic acid (PAS), a dihydrofolate reductase (DHFR) inhibitor and antituberculous agent. PAS is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity.
体内研究：
Sodium 4-aminosalicylate dihydrate
体外研究：
Sodium 4-aminosalicylate dihydrate 抑制结核分枝杆菌 H37Rv 生长，MIC 值为 0.4 μM。Sodium 4-aminosalicylate (10 μM-0.1 mM；3 h) 显著抑制牛分枝杆菌中的 rDHFR 活性。
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