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编 号:F401241
分子式:C21H22ClFN4O2
分子量:416.88
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
Halopemide is a potent phospholipase D (PLD) inhibitor, with IC50s of 220 and 310 nM for human PLD1 and PLD2, respectively. Halopemid is a dopamine receptors antagonist, and acts a psychotropic agent.

体内研究:
Halopemide (10 mg/kg; p.o.) induces dyskinesias in the majority of monkeys tested.

体外研究:
Halopemide (1-2 μM; 21 day) affects calcification in transdifferentiated MOVAS cells.
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