产品
编 号:F400642
分子式:C19H28BrNO3
分子量:398.33
产品类型
结构图
CAS No: 596-51-0
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产品详情
生物活性:
Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases.
体内研究:
Glycopyrrolate (0.005-0.01 mg/kg,静脉注射,单次给药,若心率升高低于 70 次/min 二次给药) 对麻醉犬的血压有良好的影响。Animal Model:Anesthetized dogs
Dosage:0.005mg/kg, 0.01 mg/kg
Administration:Intravenous injection (i.v.)
Result:Resulted in a significant increase in HR.Significant increased systolic, diastolic, and mean BP above baseline values.
体外研究:
Glycopyrrolate (1-10 nM, 30 min) 在豚鼠肺切片中有保护大小气道的作用。