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编 号：F399643
分子式：C16H19N3O5S.C6H14N4O2
分子式：C16H19N3O5S.C6H14N4O2
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CAS No: 59261-05-1
产品详情
生物活性：
Amoxicillin (Amoxycillin) arginine is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin arginine inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
体内研究：
Amoxicillin (Amoxycillin) arginine (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.Amoxicillin (Amoxycillin) arginine (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice.Animal Model:Female ICR/Swiss mice
Dosage:7 mg/kg
Administration:Subcutaneous injection; every 8 h, for 24 hours
Result:Inhibited bacterial numbers in a dose-dependent manner.
Animal Model:Female ICR/Swiss mice
Dosage:7 mg/kg
Administration:Subcutaneous injection; every 8 h, for 4 days
Result:Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality.
Animal Model:Swiss albino mice
Dosage:1.6 and 9.5 mg/kg
Administration:Oral administration; daily, for 7 or 14 days
Result:Improved the activity of Chlamydia trachomatis infection in mice.
体外研究：
Amoxicillin (Amoxycillin) arginine (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.
Amoxicillin (Amoxycillin) arginine is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin arginine inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
体内研究：
Amoxicillin (Amoxycillin) arginine (7 mg/kg; i.h.; female ICR/Swiss mice) inhibits strain numbers and improves the survival rate of rats in 1 mg/L or less.Amoxicillin (Amoxycillin) arginine (1.6-9.5 mg/kg; p.o.; daily, for 7 or 14 days; swiss albino mice) has against infection with chlamydia trachomatis in mice.Animal Model:Female ICR/Swiss mice
Dosage:7 mg/kg
Administration:Subcutaneous injection; every 8 h, for 24 hours
Result:Inhibited bacterial numbers in a dose-dependent manner.
Animal Model:Female ICR/Swiss mice
Dosage:7 mg/kg
Administration:Subcutaneous injection; every 8 h, for 4 days
Result:Survived all animals that were infected with organisms for which MICs were 1 mg/L or less, and with the two strains for which MICs were 2 mg/L, 20 to 40% mortality.
Animal Model:Swiss albino mice
Dosage:1.6 and 9.5 mg/kg
Administration:Oral administration; daily, for 7 or 14 days
Result:Improved the activity of Chlamydia trachomatis infection in mice.
体外研究：
Amoxicillin (Amoxycillin) arginine (1-100 μM; 24 hours; L. acidophilus) decreases living cells and increases degree of cell wall rupture in a dose-dependent manner.
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