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编 号:F399141
分子式:C17H27NO8S
分子量:347.43
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10mM*1mL in DMSO
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100mg
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生物活性:
Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia.

体内研究:
Atropine sulfate monohydrate (Tropine tropate;10 mg/kg;腹腔注射;一次,持续 40 分钟;Peromyscus sp.) 可抑制通常在麻木期间发生的心律失常。Animal Model:White-footed mice (Peromyscus sp.)
Dosage:10 mg/kg
Administration:Intraperitoneal injection; once, for 40 minutes
Result:Increased heart rate was a decrease in cardiac arrhythmia.

体外研究:
Atropine sulfate monohydrate (Tropine tropate;1 μM;肺静脉和动脉) 抑制 ACh 诱导的人肺静脉松弛。
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