产品
编 号:F398273
产品类型
结构图
CAS No: 58856-93-2
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产品详情
生物活性:
Zymosan A (Zymosan A from Saccharomyces cerevisiae) is a TLR2 agonist, that targeting TLRs can prevent and suppress IR-induced intestinal injury. Zymosan A exhibits a significant radioprotective effect, and protects IR-induced intestinal injury in mice. Zymosan A promotes the regeneration of intestinal stem cells (ISCs), after IR injury.
体内研究:
Zymosan A 可用于动物建模,构建小鼠腹膜炎模型。Zymosan A (25.0 mg/kg;腹腔注射,IR 胁迫前 12 h 和 2 h) 减轻 IR 诱导的小鼠肠道损伤。Animal Model:20.0?Gy abdominal irradiation (ABI) model in mice
Dosage:25.0?mg/kg, dissolved in NS
Administration:IP; injection at 12 and 2?h before IR
Result:Significantly reduced the degree of bleeding and edema in the intestinal tissue.