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编 号:F398089
分子式:C14H16N2O2S
分子量:276.35
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10mM*1mL in DMSO
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5mg
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10mg
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50mg
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生物活性:
C-7280948 is a selective and potent protein methyltransferase1 (PRMT1) inhibitor with an IC50 value of 12.75 μM.

体外研究:
C-7280948 is compound 6a in this article, it against hPRMT1 with an IC50 value of 12.75 μM.Especially arginine methyltransferases also target non-histone protein substrates and are therefore often called protein methyltransferases (PRMTs).The subtype PRMT1 has been linked to the activation of estrogen and androgen receptors and therefore may represent a new treatment option for hormone-dependent cancer.
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