产品
编 号：F044532
分子式：C20H36NO4P
分子量：385.48
分子式：C20H36NO4P
分子量：385.48
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 1142015-10-8
产品详情
生物活性：
FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.
体内研究：
FTY720 (S)-Phosphate (0.5 mg/kg, i.p.) preserves S1PR1 expression in mouse lungs, is protective in bleomycin-induced acute lung injury (ALI) and attenuates lung tissue leukocyte infiltration in bleomycin-injured mice.
体外研究：
FTY720 (S)-Phosphate is an agonist of S1PR1. FTY720 (S)-Phosphate (Tys, 1 μM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1, but shows no effect on inducing ubiquitination of S1PR1. FTY720 (S)-Phosphate (0.01-50 μM) also reduces β-arrestin recruitment to S1PR1.
FTY720 (S)-Phosphate is an agonist of S1P receptor 1 (S1PR1), used in the research of acute inflammatory diseases such as acute lung injury.
体内研究：
FTY720 (S)-Phosphate (0.5 mg/kg, i.p.) preserves S1PR1 expression in mouse lungs, is protective in bleomycin-induced acute lung injury (ALI) and attenuates lung tissue leukocyte infiltration in bleomycin-injured mice.
体外研究：
FTY720 (S)-Phosphate is an agonist of S1PR1. FTY720 (S)-Phosphate (Tys, 1 μM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1, but shows no effect on inducing ubiquitination of S1PR1. FTY720 (S)-Phosphate (0.01-50 μM) also reduces β-arrestin recruitment to S1PR1.
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