产品
编 号:F397992
分子式:C8H14N2O5
分子量:218.21
产品类型
结构图
CAS No: 5875-41-2
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产品详情
生物活性:
γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function.
体外研究:
γ-L-Glutamyl-L-alanine (γ-Glu-Ala) shows the potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 μM.γ-L-Glutamyl-L-alanine shows the potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 μM.γ-L-Glutamyl-L-alanine (20 μM) suppress PTH secretion from normal human parathyroid cells.γ-L-Glutamyl-L-alanine is a substrate for glutaminase B.