产品
编 号:F005012
分子式:C15H23N6O5S.C4H10O6S2.1/2C4H8O6S2
分子量:726.82
产品类型
结构图
CAS No: 101020-79-5
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产品详情
生物活性:
SAMe-1,4-Butanedisulfonate, a natural compound, is a methyl donor in the central nervous system. SAMe-1,4-Butanedisulfonate has antidepressant activity. SAMe-1,4-Butanedisulfonate can be used for research of CNS disorders.
体内研究:
SAMe-1,4-Butanedisulfonate (30 和 60 mg/kg/天,肌肉注射) 增加实验性骨关节炎兔损伤软骨的厚度和细胞密度。SAMe-1,4-Butanedisulfonate (60 和 100 mg/kg/天,肌肉注射) 保护大鼠免受 d-半乳糖胺诱导的肝损伤。SAMe-1,4-Butanedisulfonate (10-200 mg/kg,腹腔注射) 对接受强迫游泳试验 (FST) 和悬尾试验 (TST) 的小鼠表现出抗抑郁样作用。 Animal Model:Mice submitted to the forced swimming test (FST) and tail suspension test (TST)
Dosage:10, 255, 50, 100, 200 mg/kg
Administration:i.p.
Result:Reduced the immobility time in the FST and reduced the total distance traveled.