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编 号:F396162
分子式:C18H12N2O2
分子量:288.3
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生物活性:
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway.

体外研究:
Xantocillin (SD118-xanthocillin X (1)) (6.9-55.56 μM; 48 hours) has a significant inhibitory effect on the proliferation of HepG2 cells with an IC50 of 22.88 ± 4.76 μM.Xantocillin (SD118-xanthocillin X (1)) (24.3 μM; 12-48 hours) increases the expression of the autophagy-related genes, LC3, and Beclin 1.
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