产品
编 号：F044320
分子式：C54H79N11O13S2
分子量：1154.4
分子式：C54H79N11O13S2
分子量：1154.4
产品类型
规格
价格
是否有货
结构图
CAS No: 114056-26-7
产品详情
生物活性：
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior.
体内研究：
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (50-1000 ng; Intra-MPOA; 1 μL) 抑制大鼠雄性性行为的某些方面。(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (100 ng; i.c.v.; 1 μL) 可有效抑制雄性大鼠交配行为后的痛觉减退。Animal Model:Adult Long–Evans/Blue-Spruce rats
Dosage:50 ng, 200 ng, and 1 μg
Administration:Intra-MPOA (medial preoptic area) injection, 1 μL
Result:Significantly increased intromission latency and anogenital investigation at 1 μg dose. Significantly decreased intromission ratio (2) at all doses.
Animal Model:Adult male and female Long-Evans rats (8 weeks old, 220–260 g BW)
Dosage:100 ng
Administration:Intracerebroventricular injection, 1 μL
Result:Was effective in reducing pain threshold heightened by copulatory behavior.
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an oxytocin antagonist and can be used for the research of sexual behavior.
体内研究：
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (50-1000 ng; Intra-MPOA; 1 μL) 抑制大鼠雄性性行为的某些方面。(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin (100 ng; i.c.v.; 1 μL) 可有效抑制雄性大鼠交配行为后的痛觉减退。Animal Model:Adult Long–Evans/Blue-Spruce rats
Dosage:50 ng, 200 ng, and 1 μg
Administration:Intra-MPOA (medial preoptic area) injection, 1 μL
Result:Significantly increased intromission latency and anogenital investigation at 1 μg dose. Significantly decreased intromission ratio (2) at all doses.
Animal Model:Adult male and female Long-Evans rats (8 weeks old, 220–260 g BW)
Dosage:100 ng
Administration:Intracerebroventricular injection, 1 μL
Result:Was effective in reducing pain threshold heightened by copulatory behavior.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备