产品
编 号:F000856
分子式:C18H17BrN4O3
分子量:417.26
产品类型
结构图
CAS No: 1000852-17-4
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产品详情
生物活性:
Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity.
体外研究:
Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM.Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage.