产品
编 号:F395516
分子式:C22H14Cl2I2N2O2
分子量:663.07
产品类型
结构图
CAS No: 57808-65-8
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产品详情
生物活性:
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
体外研究:
Closantel, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.