产品
编 号:F395516
分子式:C22H14Cl2I2N2O2
分子量:663.07
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10mM*1mL in DMSO
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50mg
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100mg
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200mg
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500mg
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生物活性:
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

体外研究:
Closantel, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.
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