产品
编 号：F394305
分子式：C21H20O10
分子量：432.38
分子式：C21H20O10
分子量：432.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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20mg
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结构图
CAS No: 57396-78-8
产品详情
生物活性：
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence.
体外研究：
Oroxin A (0.5-100 μM；24 小时) 显著提高 PPARγ 转录水平，并在 HEK-293t 细胞中表现出最强的激活作用，浓度为 50 μM。
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity. Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence.
体外研究：
Oroxin A (0.5-100 μM；24 小时) 显著提高 PPARγ 转录水平，并在 HEK-293t 细胞中表现出最强的激活作用，浓度为 50 μM。
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