产品
编 号:F391373
分子式:C19H26O3
分子量:302.41
产品类型
结构图
CAS No: 564-35-2
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产品详情
生物活性:
11-Ketotestosterone (11-Oxotestosterone), an oxidized form of Testosterone, is an active androgen.
体内研究:
In previtellogenic cultured sterlet (Acipenser ruthenus), silastic strips embedded with 11-Ketotestosterone (5 or 25 mg/kg) are implanted in vivo for 30 days. Ovarian masculinization or sex reversal is not observed. 11-Ketotestosterone promotes sterlet ovarian development in a dose-dependent manner.
体外研究:
11-Ketotestosterone (11-KT) is a non-aromatizable and the most potent androgen in a few teleost. In vitro, after incubation with 11-Ketotestosterone (10 and 100 μM) for 5 days, both Testosterone and 17β-estradiol concentrations increased in both hepatic explants and ovarian explants culture medium; the concentration of Vitellogenin also increased in hepatic explants culture medium.