产品
编 号：F391197
分子式：C20H24N2
分子量：292.42
分子式：C20H24N2
分子量：292.42
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CAS No: 5636-83-9
产品详情
生物活性：
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents.
体内研究：
Dimethindene (0.25 mg; i.p.; once; C57BL/6 mice with skin WH) impaires cutaneous wound healing (WH) and delays skin wound closure.Animal Model:C57BL/6 mice with skin WH
Dosage:0.25 mg
Administration:intraperitoneal injection; once
Result:Delayed skin wound closure as compared to vehicle treated mice.
体外研究：
Dimethindene (5-500 μM; follicle-enclosed Xenopus oocytes) decreases Cromakalim cromakalim-induced K+ currents with an IC50 value of 29.5 μM.
Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents.
体内研究：
Dimethindene (0.25 mg; i.p.; once; C57BL/6 mice with skin WH) impaires cutaneous wound healing (WH) and delays skin wound closure.Animal Model:C57BL/6 mice with skin WH
Dosage:0.25 mg
Administration:intraperitoneal injection; once
Result:Delayed skin wound closure as compared to vehicle treated mice.
体外研究：
Dimethindene (5-500 μM; follicle-enclosed Xenopus oocytes) decreases Cromakalim cromakalim-induced K+ currents with an IC50 value of 29.5 μM.
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