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编 号:F391006
分子式:C20H24N2O5
分子量:372.41
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10mM*1mL in DMSO
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1mg
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5mg
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生物活性:
Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist, blocks α- and β-adrenergic receptors. Medroxalol shows antihypertensive and vasodilating effects.

体内研究:
Medroxalol (oral gavage; 12.5-50 mg/kg; once daily; 12 d) treatment shows antihypertensive activity in spontaneously hypertensive rats.Animal Model:Male spontaneously hypertensive rats (SHR)
Dosage:12.5, 25, or 50 mg/kg
Administration:Oral gavage; 12.5, 25, or 50 mg/kg; once daily; 12 days
Result:Produced a dose-related fall in blood pressure.

体外研究:
Medroxalol (0.1-10 μM; 20 min) shows α- and β-adrenergic receptor antagonism in isolated rabbit aortic strip.
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