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编 号:F004915
分子式:C23H20N2O4S
分子量:420.48
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生物活性:
Desethyl KBT-3022 is the main active metabolite of the new antiplatelet agent, KBT-3022.

体外研究:
Pretreatment with desethyl KBT-3022 0.1, 0.3 and 1 mg/kg, i.v. prolongs the time required to achieve thrombotic occlusion in the femoral artery and inhibits collagen-induced platelet aggregation in whole blood ex vivo, each in a dose-dependent manner. Desethyl KBT-3022 inhibits the thrombin-induced aggregation of washed platelets in a concentration-dependent manner 1–40 μM.
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