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编 号:F390047
分子式:C20H23ClO3
分子量:346.85
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生物活性:
Beclobrate (Sgd 24774), a Fibric acid derivative, displays remarkable lipid lowering activity in rodents.

体内研究:
On the normal diet rats, Beclobrate lowers total plasma cholesterol by 22-33.4% (10-50 mg/kg); the cholesterol reduction occurred mainly in high density lipoproteins (HDL). In addition, Beclobrate administration dramatically increases the activity of the high-affinity receptors for beta-VLDL in isolated liver membranes.
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