产品
编 号：F389843
分子式：C10H8BrNO2S2
分子量：318.21
分子式：C10H8BrNO2S2
分子量：318.21
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 55854-43-8
产品详情
生物活性：
ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings.
体外研究：
ES9-17 (0-100 μM; 30 分钟) 抑制亲脂性苯乙烯基内吞示踪剂 (FM4-64) 的吸收，EC50 为 13 μM。ES9-17 (30 μM; 30分钟) 不会消耗拟南芥细胞的 ATP。ES9-17 (30 μM; 30分钟) 也降低了 HeLa 细胞中转铁蛋白的摄取。ES9-17 靶向 CHC，调控内膜运输途径，不引起细胞质酸化。
ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings.
体外研究：
ES9-17 (0-100 μM; 30 分钟) 抑制亲脂性苯乙烯基内吞示踪剂 (FM4-64) 的吸收，EC50 为 13 μM。ES9-17 (30 μM; 30分钟) 不会消耗拟南芥细胞的 ATP。ES9-17 (30 μM; 30分钟) 也降低了 HeLa 细胞中转铁蛋白的摄取。ES9-17 靶向 CHC，调控内膜运输途径，不引起细胞质酸化。
产品资料
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