产品
编 号:F389625
分子式:C9H18N2O2
分子量:186.25
产品类型
结构图
CAS No: 5579-13-5
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产品详情
生物活性:
Capuride is an orally active sedative agent. Capuride has anticonvulsant activity.
体内研究:
Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats.Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg.Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in6 Hz Psychomotor seizure mice.Animal Model:Electrically (MES) and chemically (scMet) induced seizures in rats
Dosage:38-107 mg/kg
Administration:Oral administration (p.o.)
Result:ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model).